Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 4/20 | 0.68 |
| ▸ | ACHE | P22303 | 3/20 | 0.67 |
| ▸ | AR | P10275 | 2/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724495 | 1.00 | MAOB (0.71) | MAOBCA12CA1CA2CA4 | |
| SCHEMBL5617809 | 0.85 | MAOB (0.68) | MAOBCA12CA1CA2CA4 | |
| SCHEMBL29724370 | 0.85 | MAOB (0.68) | MAOBCA12CA1CA2CA4 | |
| SCHEMBL28441804 | 0.85 | MAOB (0.68) | MAOBCA12CA1CA2CA4 | |
| SCHEMBL29724361 | 0.81 | AR (0.68) | MAOBMAOAARSLC16A3 | |
| SCHEMBL28438618 | 0.81 | AR (0.68) | MAOBMAOAARSLC16A3 | |
| SCHEMBL28440199 | 0.81 | MAOB (1.00) | MAOBCA12CA1CA2CA4 | |
| SCHEMBL29724665 | 0.81 | MAOB (1.00) | MAOBCA12CA1CA2CA4 | |
| SCHEMBL7862342 | 0.81 | NPC1 (0.64) | MAOBMAOAACHENPC1RAB9A | |
| SCHEMBL7436425 | 0.81 | MAOB (0.82) | MAOBMAOAACHEARCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533721-B | Benzopyrone or quinolinone compounds and application thereof | 浙江大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-111533721-A | Benzopyrone or quinolinone compounds and application thereof | 浙江大学 | 2020-08-14 | — | — | CN | disclosed |