Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28443785 | 1.00 | DPP4 (0.42) | DPP4OPRM1OPRD1CHRM2CHRM4 | |
| SCHEMBL30377259 | 1.00 | DPP4 (0.42) | DPP4OPRM1OPRD1CHRM2CHRM4 | |
| SCHEMBL23043070 | 0.85 | CHRM2 (0.42) | CHRM2CHRM4CHRM3KMT2ACHRNB2 | |
| SCHEMBL13567693 | 0.85 | DPP4 (0.43) | DPP4CHRM2CHRM4CHRM3KMT2A | |
| Hydrochloric Acid SCHEMBL15819318 | 0.83 | DPP4 (0.42) | DPP4CHRM2CHRM4CHRM3KMT2A | |
| SCHEMBL30952261 | 0.83 | CHRM2 (0.38) | DPP4CHRM2CHRM4CHRM3KMT2A | |
| Hydrochloric Acid SCHEMBL15390247 | 0.83 | DPP4 (0.42) | DPP4CHRM2CHRM4CHRM3KMT2A | |
| SCHEMBL3803832 | 0.82 | DPP4 (0.43) | DPP4OPRM1OPRD1 | |
| SCHEMBL6285170 | 0.81 | CHRM2 (0.42) | CHRM2CHRM4CHRM3KMT2ACHRNB2 | |
| SCHEMBL6513544 | 0.81 | CHRM2 (0.42) | CHRM2CHRM4CHRM3KMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606970-B | 1, 5-diazabicyclo [5,3,0] decarenone amino acid derivative and preparation method and application thereof | 中国药科大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-111606970-A | 1, 5-diazabicyclo [5,3,0] deca-alkanone amino acid derivative and preparation method and application thereof | 中国药科大学 | 2020-09-01 | — | — | CN | disclosed |