Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 1.00 |
| ▸ | MAOA | P21397 | 7/20 | 1.00 |
| ▸ | AR | P10275 | 2/20 | 1.00 |
| ▸ | ACHE | P22303 | 8/20 | 0.80 |
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | RAB9A | P51151 | 3/20 | 0.79 |
| ▸ | CASP3 | P42574 | 2/20 | 0.79 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.79 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.79 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724368 | 1.00 | MAOB (1.00) | MAOBMAOAARACHENPC1 | |
| SCHEMBL16334580 | 0.90 | NPC1 (0.83) | MAOBMAOAARACHENPC1 | |
| SCHEMBL16334329 | 0.88 | NPC1 (1.00) | MAOBMAOAARACHENPC1 | |
| SCHEMBL16334352 | 0.87 | NPC1 (0.79) | MAOBMAOAARACHENPC1 | |
| SCHEMBL16580069 | 0.87 | NPC1 (0.79) | MAOBMAOAARACHENPC1 | |
| SCHEMBL16334073 | 0.87 | MAOB (0.80) | MAOBMAOAARACHENPC1 | |
| SCHEMBL107774 | 0.87 | MAOB (1.00) | MAOBMAOAARACHENPC1 | |
| SCHEMBL29382160 | 0.87 | MAOB (1.00) | MAOBMAOAARACHENPC1 | |
| SCHEMBL19754928 | 0.86 | MAOB (0.74) | MAOBMAOAARACHENPC1 | |
| SCHEMBL5617810 | 0.85 | NPC1 (0.76) | MAOBMAOAARACHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533721-B | Benzopyrone or quinolinone compounds and application thereof | 浙江大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-111533721-A | Benzopyrone or quinolinone compounds and application thereof | 浙江大学 | 2020-08-14 | — | — | CN | disclosed |