Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 17/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121043 | 0.87 | PTGS1 (0.58) | PTGS1PTGS2CYP17A1 | |
| SCHEMBL28450051 | 0.84 | PTGS1 (0.50) | PTGS1PTGS2CYP17A1SLC22A12 | |
| SCHEMBL28457565 | 0.80 | PTGS1 (0.61) | PTGS1PTGS2SLC22A12 | |
| SCHEMBL28448101 | 0.80 | SLC22A12 (0.48) | PTGS1PTGS2CYP17A1SLC22A12 | |
| SCHEMBL28448368 | 0.79 | SLC22A12 (0.50) | PTGS1PTGS2SLC22A12 | |
| SCHEMBL521538 | 0.73 | PTGS1 (0.60) | PTGS1PTGS2SLC22A12 | |
| SCHEMBL14830652 | 0.71 | CYP17A1 (0.53) | PTGS1PTGS2CYP17A1SLC22A12 | |
| SCHEMBL14960632 | 0.70 | PTGS1 (0.67) | PTGS1PTGS2 | |
| SCHEMBL527008 | 0.70 | CYP17A1 (0.73) | PTGS1PTGS2CYP17A1 | |
| SCHEMBL14627251 | 0.70 | PTGS1 (0.53) | PTGS1PTGS2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831556-B | Sulfonamide compound, preparation method thereof and application of sulfonamide compound as urate transporter inhibitor medicine | 成都海创药业有限公司 | 2020-09-01 | — | — | CN | disclosed |