SCHEMBL28445191

SCHEMBL28445191

CC(C)C1=CC([Zr])c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.41
POLB P06746 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
GPR3 P46089 2/20 0.38
CDC25A P30304 1/20 0.35
CDC25B P30305 1/20 0.35
HTR2A P28223 2/20 0.33
SLC6A4 P31645 3/20 0.32
SLC6A3 Q01959 3/20 0.32
SLC6A2 P23975 2/20 0.32
ACHE P22303 2/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD1 P21728 1/20 0.32
ADRA1A P35348 1/20 0.32
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6910275 0.98 PTPN1 (0.40) PTPN1POLBMEN1KMT2AATM
SCHEMBL28446639 0.83 TSHR (0.36) PTPN1POLBMEN1KMT2AATM
Hydrochloric Acid SCHEMBL4430821 0.74 PTPN1 (0.40) PTPN1POLBMEN1KMT2AATM
SCHEMBL6401846 0.74 PTPN1 (0.40) PTPN1POLBMEN1KMT2AATM
Hydrochloric Acid SCHEMBL5595927 0.73 PTPN1 (0.39) PTPN1POLBMEN1KMT2AATM
SCHEMBL28441987 0.73 PTPN1 (0.39) PTPN1POLBMEN1KMT2AATM
SCHEMBL5702762 0.73 PTPN1 (0.39) PTPN1POLBMEN1KMT2AATM
Ethylene SCHEMBL10454686 0.72 PTPN1 (0.38) PTPN1POLBMEN1KMT2AATM
SCHEMBL6903188 0.72 PTPN1 (0.38) PTPN1POLBMEN1KMT2AATM
SCHEMBL21034911 0.71 PTPN1 (0.37) PTPN1POLBMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111417657-B Asymmetric ansa-metallocene catalyst compounds for the preparation of polyolefins having broad molecular weight distribution 埃克森美孚化学专利公司 2022-11-25 CN disclosed
CN-111417657-A Asymmetric ansa-metallocene catalyst compounds for the preparation of polyolefins having broad molecular weight distribution 埃克森美孚化学专利公司 2020-07-14 CN disclosed