Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449198 | 0.90 | STAT3 (0.70) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28445495 | 0.87 | STAT3 (0.62) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28457265 | 0.87 | STAT3 (0.61) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28451587 | 0.86 | STAT3 (0.61) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28445920 | 0.85 | STAT3 (0.60) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28444274 | 0.85 | STAT3 (0.58) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28453176 | 0.85 | STAT3 (0.62) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28445524 | 0.85 | STAT3 (0.59) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28451575 | 0.84 | STAT3 (0.64) | STAT3ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL28451230 | 0.84 | STAT3 (0.67) | STAT3ALDH1A1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191885-B | Piperidinothiophene micromolecule organic compound and application thereof | 华东师范大学 | 2020-08-04 | — | — | CN | claimed |
| CN-108191885-B | Piperidinothiophene micromolecule organic compound and application thereof | 华东师范大学 | 2020-08-04 | — | — | CN | disclosed |