Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 15/20 | 0.50 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66723 | 0.94 | CACNA1B (0.46) | CACNA1BACACBGRIN2B | |
| SCHEMBL66587 | 0.87 | CACNA1B (0.59) | CACNA1BACACBGRIN2B | |
| SCHEMBL1336427 | 0.85 | CACNA1B (0.59) | CACNA1BACACBGRIN2B | |
| SCHEMBL66722 | 0.84 | CACNA1B (0.44) | CACNA1BACACBGRIN2B | |
| SCHEMBL2843378 | 0.83 | CACNA1B (0.54) | CACNA1BACACB | |
| SCHEMBL3249607 | 0.83 | CACNA1B (0.54) | CACNA1BACACB | |
| SCHEMBL1336979 | 0.83 | CACNA1B (0.46) | CACNA1BACACBGRIN2B | |
| SCHEMBL1334987 | 0.83 | CACNA1B (0.69) | CACNA1BACACB | |
| SCHEMBL1335911 | 0.82 | CACNA1B (0.58) | CACNA1BACACBGRIN2B | |
| SCHEMBL1337059 | 0.82 | CACNA1B (0.61) | CACNA1BACACBGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130558-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2010-05-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130558-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | CACNA1C, ORAI1, CACNA1S | CACNA1B 5/4885ACACB 2352/4885GRIN2B 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.