Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 8/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 8/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537279 | 0.86 | SYK (0.56) | SYKBRD4CDK1EGFRSRC | |
| SCHEMBL4178458 | 0.86 | SYK (0.56) | SYKBRD4CDK1EGFRSRC | |
| SCHEMBL12518613 | 0.85 | SYK (0.71) | SYKBRD4EGFRITKMET | |
| SCHEMBL4180112 | 0.85 | SYK (0.57) | SYKBRD4CDK1EGFRSRC | |
| SCHEMBL9923768 | 0.84 | SYK (0.56) | SYKBRD4CDK1EGFRSRC | |
| SCHEMBL30306552 | 0.84 | SYK (0.56) | SYKBRD4CDK1EGFRSRC | |
| SCHEMBL28444667 | 0.84 | SYK (0.59) | SYKBRD4EGFRITKMET | |
| SCHEMBL4166343 | 0.83 | SYK (0.55) | SYKBRD4CDK1EGFRSRC | |
| SCHEMBL29537421 | 0.83 | SYK (0.55) | SYKBRD4CDK1EGFRSRC | |
| SCHEMBL29537952 | 0.83 | SYK (0.55) | SYKBRD4CDK1EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384694-B | Substituted aminopyrimidine derivative and preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2020-09-04 | — | — | CN | disclosed |