SCHEMBL28446602

SCHEMBL28446602

CC(C)(C)C(=O)C(=O)O.[CaH2]

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271740 0.96
SCHEMBL28232356 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL28058978 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL28233227 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL2390662 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R
Ammonia Solution, Strong SCHEMBL3498578 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R
Water SCHEMBL11633420 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL28232349 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL28232400 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL27655275 0.93 TSHR (0.47) TSHRALDH1A1HMGCRCHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108384210-B Application of pyruvate and modified polylactic acid 中国科学院长春应用化学研究所 2020-07-28 CN claimed
CN-108384210-B Application of pyruvate and modified polylactic acid 中国科学院长春应用化学研究所 2020-07-28 CN disclosed