Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 18/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 13/20 | 0.57 |
| ▸ | PSMB2 | P49721 | 13/20 | 0.57 |
| ▸ | PSMB8 | P28062 | 12/20 | 0.57 |
| ▸ | PSMB9 | P28065 | 12/20 | 0.57 |
| ▸ | PSMB6 | P28072 | 12/20 | 0.57 |
| ▸ | PSMB10 | P40306 | 12/20 | 0.57 |
| ▸ | PSMB11 | A5LHX3 | 11/20 | 0.57 |
| ▸ | PSMA7 | O14818 | 11/20 | 0.57 |
| ▸ | PSMA1 | P25786 | 11/20 | 0.57 |
| ▸ | PSMA2 | P25787 | 11/20 | 0.57 |
| ▸ | PSMA3 | P25788 | 11/20 | 0.57 |
| ▸ | PSMA4 | P25789 | 11/20 | 0.57 |
| ▸ | PSMA5 | P28066 | 11/20 | 0.57 |
| ▸ | PSMB4 | P28070 | 11/20 | 0.57 |
| ▸ | PSMB3 | P49720 | 11/20 | 0.57 |
| ▸ | PSMA6 | P60900 | 11/20 | 0.57 |
| ▸ | PSMA8 | Q8TAA3 | 11/20 | 0.57 |
| ▸ | PSMB7 | Q99436 | 11/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969555 | 0.83 | PSMB5 (0.68) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL18114334 | 0.82 | PSMB5 (0.73) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL18114332 | 0.82 | PSMB5 (0.73) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL20257210 | 0.80 | PSMB5 (0.63) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL30731585 | 0.79 | PSMB5 (0.71) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL20510120 | 0.79 | PSMB5 (0.71) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL20257209 | 0.79 | PSMB5 (0.71) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL22757736 | 0.77 | PSMB5 (0.68) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL29359705 | 0.77 | PSMB5 (0.57) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL23969556 | 0.77 | PSMB5 (0.57) | PSMB5PSMB1PSMB2PSMB8PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794520-B | Synthesis method of boric acid citrate compounds including Eszolomide | 北京大学 | 2020-07-24 | — | — | CN | claimed |
| CN-108794520-B | Synthesis method of boric acid citrate compounds including Eszolomide | 北京大学 | 2020-07-24 | — | — | CN | disclosed |
| CN-108794520-B | Synthesis method of boric acid citrate compounds including Eszolomide | 北京大学 | 2020-07-24 | — | — | CN | disclosed |