Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 2/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.55 |
| ▸ | ITGAL | P20701 | 2/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.51 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.48 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23279667 | 0.90 | ITGB2 (0.59) | ITGB2ICAM1ITGALPSMB5ITGB1 | |
| SCHEMBL22370286 | 0.88 | PSMB5 (0.50) | ITGB2ICAM1ITGALPSMB5PSMB11 | |
| SCHEMBL22370283 | 0.88 | PSMB5 (0.50) | ITGB2ICAM1ITGALPSMB5PSMB11 | |
| SCHEMBL23279661 | 0.86 | ITGB2 (0.55) | ITGB2ICAM1ITGALPSMB5ITGB1 | |
| SCHEMBL23279660 | 0.86 | ITGB2 (0.55) | ITGB2ICAM1ITGALPSMB5ITGB1 | |
| SCHEMBL22370671 | 0.84 | ITGB1 (0.54) | ITGB2ICAM1ITGALPSMB5ITGB1 | |
| SCHEMBL22370674 | 0.84 | ITGB1 (0.54) | ITGB2ICAM1ITGALPSMB5ITGB1 | |
| SCHEMBL30949850 | 0.84 | ITGB1 (0.54) | ITGB2ICAM1ITGALPSMB5ITGB1 | |
| SCHEMBL28447775 | 0.82 | MEN1 (0.53) | ITGB2ICAM1ITGALPSMB5ITGB1 | |
| SCHEMBL24008818 | 0.79 | PSMB5 (0.60) | ITGB2ICAM1ITGALPSMB5PSMB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491938-B | Immunoproteasome inhibitors | 普林斯匹亚生物制药公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-111491938-A | Immunoproteasome inhibitors | 普林斯匹亚生物制药公司 | 2020-08-04 | — | — | CN | disclosed |