Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.61 |
| ▸ | ADA | P00813 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PI4KA | P42356 | 2/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.59 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.59 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.59 |
| ▸ | GAPDH | P04406 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | STAT6 | P42226 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745554 | 1.00 | EGFR (0.61) | EGFRERBB2ADAADORA3ADORA2A | |
| SCHEMBL21133221 | 1.00 | EGFR (0.61) | EGFRERBB2ADAADORA3ADORA2A | |
| SCHEMBL27272946 | 1.00 | EGFR (0.61) | EGFRERBB2ADAADORA3ADORA2A | |
| SCHEMBL4745556 | 1.00 | EGFR (0.61) | EGFRERBB2ADAADORA3ADORA2A | |
| SCHEMBL5199003 | 0.87 | HIF1A (0.56) | EGFRERBB2ADAHIF1A | |
| SCHEMBL5198998 | 0.87 | HIF1A (0.56) | EGFRERBB2ADAHIF1A | |
| SCHEMBL23982189 | 0.87 | ADA (0.62) | EGFRERBB2ADAADORA3ADORA2A | |
| Deoxyadenosine SCHEMBL12222478 | 0.87 | HIF1A (0.71) | ADAADORA3ADORA2AADORA2BSMN1; SMN2 | |
| Deoxyadenosine SCHEMBL21637036 | 0.87 | HIF1A (0.71) | ADAADORA3ADORA2AADORA2BSMN1; SMN2 | |
| Deoxyadenosine SCHEMBL19877 | 0.87 | HIF1A (0.71) | ADAADORA3ADORA2AADORA2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010916-B | Phosphoramidate derivatives of nucleoside compounds and uses thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-112010916-A | Phosphoramidate derivatives of nucleoside compounds and uses thereof | 广东东阳光药业有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-111565726-A | Compositions and methods for modulating immune responses by activating alpha protein kinase 1 | 上海药苑生物科技有限公司 | 2020-08-21 | — | — | CN | disclosed |