Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22495287 | 0.89 | MAPT (0.56) | MAPTTSHRKMT2ANPC1RAB9A | |
| SCHEMBL28453259 | 0.84 | MAPT (0.61) | MAPTTSHRKMT2ANPC1RAB9A | |
| SCHEMBL22495241 | 0.84 | MAPT (0.60) | MAPTTSHRKMT2ANPC1RAB9A | |
| SCHEMBL22495256 | 0.75 | MAPT (0.54) | MAPTTSHRKMT2AMEN1MAPK1 | |
| SCHEMBL30172105 | 0.75 | MAPT (0.54) | MAPTTSHRKMT2AMEN1MAPK1 | |
| SCHEMBL22495260 | 0.74 | MAPT (0.58) | MAPTTSHRKMT2ANPC1RAB9A | |
| SCHEMBL22495387 | 0.74 | MAPT (0.58) | MAPTTSHRKMT2ANPC1RAB9A | |
| SCHEMBL31504277 | 0.74 | KMT2A (0.54) | MAPTTSHRKMT2ANPC1RAB9A | |
| SCHEMBL22495397 | 0.74 | KMT2A (0.54) | MAPTTSHRKMT2ANPC1RAB9A | |
| SCHEMBL2306331 | 0.74 | MAPT (0.60) | MAPTTSHRKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511732-A | Radiolabelled compounds | 豪夫迈·罗氏有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-111511732-A | Radiolabelled compounds | 豪夫迈·罗氏有限公司 | 2020-08-07 | — | — | CN | disclosed |