Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.86 |
| ▸ | LMNA | P02545 | 7/20 | 0.86 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.86 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.86 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.86 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.86 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.86 |
| ▸ | HTT | P42858 | 2/20 | 0.86 |
| ▸ | POLB | P06746 | 2/20 | 0.86 |
| ▸ | NPC1 | O15118 | 2/20 | 0.86 |
| ▸ | HPGD | P15428 | 2/20 | 0.86 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354223 | 0.93 | MAPT (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL272189 | 0.93 | MAPT (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL31319486 | 0.93 | MAPT (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL272188 | 0.93 | MAPT (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL23392582 | 0.91 | MAPT (0.97) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL19350416 | 0.91 | MAPT (0.97) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL30440648 | 0.91 | MAPT (0.97) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL27840093 | 0.91 | MAPT (0.97) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL16931517 | 0.91 | MAPT (0.97) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Chloroform SCHEMBL28574623 | 0.87 | MAPT (0.89) | MAPTLMNAL3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111579510-A | Light sensing film and method for rapidly, quantitatively and selectively detecting Cd (II), Cu (II) and Zn (II) | 西安建筑科技大学 | 2020-08-25 | — | — | CN | claimed |
| CN-111579510-A | Light sensing film and method for rapidly, quantitatively and selectively detecting Cd (II), Cu (II) and Zn (II) | 西安建筑科技大学 | 2020-08-25 | — | — | CN | disclosed |