Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850988 | 0.93 | TLR7 (0.62) | TLR7TLR8 | |
| SCHEMBL4208172 | 0.89 | TLR7 (0.74) | TLR7TLR8 | |
| SCHEMBL4208166 | 0.89 | TLR7 (0.74) | TLR7TLR8 | |
| SCHEMBL2848962 | 0.87 | TLR7 (0.67) | TLR7 | |
| SCHEMBL2850581 | 0.85 | TLR7 (0.71) | TLR7 | |
| SCHEMBL4203333 | 0.84 | TLR7 (0.75) | TLR7TLR8 | |
| SCHEMBL4203329 | 0.84 | TLR7 (0.75) | TLR7TLR8 | |
| SCHEMBL4212483 | 0.82 | TLR7 (0.74) | TLR7TLR8 | |
| SCHEMBL4212489 | 0.82 | TLR7 (0.74) | TLR7TLR8 | |
| SCHEMBL2851011 | 0.80 | TLR7 (0.70) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222648-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS | AstraZeneca AB (SE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009067081-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS | ASTRAZENECA AB (SE) | 2009-05-28 | — | — | WO | disclosed |