Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28463720 | 0.87 | TP53 (0.46) | HTTKDM4EKMT2AMAPK1HPGD | |
| SCHEMBL28455576 | 0.86 | TP53 (0.51) | MAPK1PDE4D | |
| SCHEMBL30151541 | 0.86 | MAPK1 (0.50) | EGFRHTTKDM4EKMT2ALMNA | |
| SCHEMBL28450295 | 0.85 | PRSS1 (0.54) | KDM4EMAPK1HPGD | |
| SCHEMBL28458940 | 0.84 | MAPT (0.43) | HTTKDM4EKMT2ALMNARAB9A | |
| SCHEMBL20463365 | 0.81 | HTT (0.49) | EGFRHTTKDM4EKMT2ALMNA | |
| SCHEMBL2590444 | 0.81 | HTT (0.66) | EGFRHTTKDM4EKMT2ALMNA | |
| SCHEMBL25315062 | 0.80 | MAPT (0.50) | EGFRHTTKDM4EKMT2ALMNA | |
| SCHEMBL20463473 | 0.80 | EGFR (0.47) | EGFRHTTKDM4EKMT2ALMNA | |
| SCHEMBL22386752 | 0.78 | HTT (0.48) | EGFRHTTKDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041331-B | Styrylxanthine derivative and use thereof | 广东东阳光药业有限公司 | 2020-08-07 | — | — | CN | disclosed |