Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456337 | 1.00 | BACE1 (0.66) | BACE1HTTALDH1A1HPGDPKM | |
| SCHEMBL1607531 | 0.86 | HTT (0.79) | BACE1HTTALDH1A1HPGDPKM | |
| SCHEMBL30392187 | 0.86 | HTT (0.79) | BACE1HTTALDH1A1HPGDPKM | |
| SCHEMBL8011241 | 0.83 | BACE1 (0.79) | BACE1HTTALDH1A1HPGDPTPN1 | |
| SCHEMBL1587245 | 0.82 | BACE1 (0.81) | BACE1HTTALDH1A1HPGDPTPN1 | |
| SCHEMBL8009478 | 0.82 | BACE1 (0.81) | BACE1HTTALDH1A1HPGDPTPN1 | |
| SCHEMBL1586722 | 0.82 | BACE1 (0.81) | BACE1HTTALDH1A1HPGDPTPN1 | |
| SCHEMBL30392401 | 0.82 | BACE1 (0.81) | BACE1HTTALDH1A1HPGDPTPN1 | |
| SCHEMBL1586724 | 0.82 | BACE1 (0.81) | BACE1HTTALDH1A1HPGDPTPN1 | |
| SCHEMBL10871362 | 0.78 | CA12 (0.49) | BACE1HTTALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108265007-B | Deep-sea fungus 3A00421 and application of fermentation compound thereof | 国家海洋局第三海洋研究所 | 2020-09-22 | — | — | CN | disclosed |