Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.78 |
| ▸ | THRB | P10828 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL584921 | 1.00 | — | — | |
| Hexane SCHEMBL1134655 | 1.00 | — | — | |
| Pentadecane SCHEMBL9512192 | 0.94 | TSHR (0.89) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL10596554 | 0.94 | TSHR (0.89) | TSHRTHRBLMNASLC22A1DNM1 | |
| Heptane SCHEMBL8376122 | 0.94 | — | — | |
| Decane SCHEMBL10596550 | 0.94 | TSHR (0.89) | TSHRTHRBLMNASLC22A1DNM1 | |
| Tetradecane SCHEMBL190484 | 0.94 | TSHR (0.89) | TSHRTHRBLMNASLC22A1DNM1 | |
| Heptane SCHEMBL9289755 | 0.94 | TSHR (0.89) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL22325573 | 0.94 | TSHR (0.89) | TSHRTHRBLMNASLC22A1DNM1 | |
| Heptane SCHEMBL1134664 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115607544-A | Sacubitril valsartan sodium sustained-release composition, preparation method and application thereof | 上海博志研新药物技术有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-112641742-B | Sacubitril valsartan sodium sustained-release tablet and preparation method thereof | 南京康川济医药科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-115337278-A | Preparation method of pharmaceutical composition containing Sacubitril sodium and valsartan sodium | 常州制药厂有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-107980038-B | Calcium salt of Shakuba Trigonella | 诺华股份有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-112641742-A | Sacubitril valsartan sodium sustained-release tablet and preparation method thereof | 南京康川济医药科技有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-109265406-B | New crystal form of Sacubitril valsartan sodium and preparation method and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2020-09-22 | — | — | CN | disclosed |