Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.74 |
| ▸ | ABL1 | P00519 | 17/20 | 0.74 |
| ▸ | EGFR | P00533 | 15/20 | 0.74 |
| ▸ | HCK | P08631 | 14/20 | 0.74 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.74 |
| ▸ | KDR | P35968 | 14/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.74 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.74 |
| ▸ | PRKDC | P78527 | 14/20 | 0.74 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.74 |
| ▸ | MTOR | P42345 | 13/20 | 0.74 |
| ▸ | EPHB4 | P54760 | 13/20 | 0.74 |
| ▸ | PI4KB | Q9UBF8 | 12/20 | 0.74 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.61 |
| ▸ | CSK | P41240 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451646 | 0.86 | ABL1 (0.69) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL2469676 | 0.85 | SRC (1.00) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL24096879 | 0.84 | SRC (0.69) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL24096736 | 0.84 | SRC (0.72) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL29388023 | 0.83 | SRC (1.00) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL12437010 | 0.83 | SRC (1.00) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL2433214 | 0.82 | SRC (1.00) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL14574665 | 0.81 | SRC (0.87) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL2468434 | 0.81 | SRC (0.83) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL1319283 | 0.81 | SRC (0.69) | SRCABL1EGFRHCKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606910-A | Synthesis process of antitumor drug Sapanisiertib | 药璞(上海)医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |