Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 10/20 | 0.62 |
| ▸ | DRD5 | P21918 | 9/20 | 0.62 |
| ▸ | DRD2 | P14416 | 8/20 | 0.56 |
| ▸ | DRD3 | P35462 | 8/20 | 0.56 |
| ▸ | DRD4 | P21917 | 6/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525452 | 0.91 | DRD1 (0.57) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL10673137 | 0.85 | DRD1 (0.52) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29500325 | 0.85 | MAOB (0.70) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL16827433 | 0.85 | MAOB (0.70) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29500341 | 0.85 | EED (0.59) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29500309 | 0.85 | DRD1 (0.52) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL2948505 | 0.84 | AKR1C3 (0.56) | DRD1DRD5DRD2DRD3MAOB | |
| SCHEMBL29500368 | 0.84 | DRD1 (0.51) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL30296979 | 0.83 | DRD1 (0.56) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL27806895 | 0.83 | DRD1 (0.56) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285804-B | Method for synthesizing thioamide compound | 广州中医药大学(广州中医药研究院) | 2022-01-07 | — | — | CN | claimed |
| CN-111285804-A | Method for synthesizing thioamide compound | 广州中医药大学(广州中医药研究院) | 2020-06-16 | — | — | CN | claimed |
| CN-111285804-B | Method for synthesizing thioamide compound | 广州中医药大学(广州中医药研究院) | 2022-01-07 | — | — | CN | disclosed |
| CN-111285804-A | Method for synthesizing thioamide compound | 广州中医药大学(广州中医药研究院) | 2020-06-16 | — | — | CN | disclosed |