Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29691444 | 0.92 | CA1 (0.46) | CA1EPHX1PPARAADH1BADH1A | |
| Sulfuric Acid SCHEMBL28626973 | 0.92 | CA1 (0.46) | CA1EPHX1PPARAADH1BADH1A | |
| SCHEMBL28108402 | 0.82 | EPHX1 (0.64) | CA1EPHX1PPARACA2S1PR2 | |
| SCHEMBL8419391 | 0.82 | CA1 (0.39) | CA1EPHX1PPARAADH1BADH1A | |
| SCHEMBL11143687 | 0.81 | EPHX1 (0.36) | CA1EPHX1CA2S1PR2S1PR4 | |
| SCHEMBL28191297 | 0.80 | PAOX (0.50) | CA1EPHX1PPARAADH1BADH1A | |
| Dimethylamine SCHEMBL27659636 | 0.78 | — | — | |
| SCHEMBL3435 | 0.78 | — | — | |
| Acetone SCHEMBL7081095 | 0.77 | — | — | |
| Sulfuric Acid SCHEMBL31147697 | 0.76 | EPHX1 (0.70) | CA1EPHX1PPARACA2S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115138213-B | Preparation method of pervaporation membrane and method for removing water and phosgene in organic solvent | 万华化学（宁波）有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-111298660-B | Preparation method of anti-fouling composite nanofiltration membrane with strong stability | 浙江理工大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-111298660-A | Preparation method of anti-fouling composite nanofiltration membrane with strong stability | 浙江理工大学 | 2020-06-19 | — | — | CN | disclosed |