Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND3 | P30281 | 14/20 | 0.83 |
| ▸ | CDK6 | Q00534 | 14/20 | 0.83 |
| ▸ | CCNK | O75909 | 12/20 | 0.83 |
| ▸ | CDK9 | P50750 | 12/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.83 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.73 |
| ▸ | CDK2 | P24941 | 2/20 | 0.73 |
| ▸ | CTSC | P53634 | 2/20 | 0.62 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.62 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870807 | 0.91 | CCND3 (1.00) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL28467962 | 0.91 | CCND3 (1.00) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL30395291 | 0.87 | CCND3 (1.00) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL28465104 | 0.87 | CCND3 (0.75) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL30395432 | 0.86 | CCND3 (1.00) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL30395223 | 0.85 | CCND3 (1.00) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL30394485 | 0.84 | CCND3 (1.00) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL30395224 | 0.84 | CCND3 (1.00) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL31684756 | 0.83 | CCND3 (0.69) | CCND3CDK6CCNKCDK9CYP3A4 | |
| SCHEMBL31684799 | 0.83 | MAP3K7 (0.72) | CCND3CDK6CCNKCDK9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620852-B | 5-chloro-pyrimidine-2, 4-diamine compound, and preparation method and application thereof | 镇江植生源农业科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-111620852-A | 5-chloro-pyrimidine-2, 4-diamine compound and preparation method and application thereof | 南京迪维奥医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |