Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190240 | 0.84 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL12188002 | 0.81 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL637250 | 0.81 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL8038687 | 0.81 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Venlafaxine SCHEMBL6872633 | 0.81 | SLC6A2 (0.97) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Venlafaxine SCHEMBL6554144 | 0.81 | SLC6A2 (0.97) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Hydrogen Sulfide SCHEMBL28158135 | 0.80 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL14224708 | 0.80 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Hydrochloric Acid SCHEMBL3325847 | 0.80 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL5815212 | 0.80 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159330-A | Preparation method of venlafaxine hydrochloride intermediate | 苏州第四制药厂有限公司 | 2021-01-01 | — | — | CN | claimed |
| CN-111675671-A | Preparation method of venlafaxine impurity E | 苏州第四制药厂有限公司 | 2020-09-18 | — | — | CN | claimed |
| CN-112159330-A | Preparation method of venlafaxine hydrochloride intermediate | 苏州第四制药厂有限公司 | 2021-01-01 | — | — | CN | disclosed |
| CN-108752235-B | Method for preparing drug intermediate by hydrotalcite material catalysis | 武汉普元药业有限责任公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-108752235-B | Method for preparing drug intermediate by hydrotalcite material catalysis | 武汉普元药业有限责任公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-111675671-A | Preparation method of venlafaxine impurity E | 苏州第四制药厂有限公司 | 2020-09-18 | — | — | CN | disclosed |