Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.78 |
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.62 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23694846 | 0.89 | GPBAR1 (0.82) | NR1H4GPBAR1CYP3A4PDE3ALMNA | |
| SCHEMBL8226086 | 0.89 | GPBAR1 (0.82) | NR1H4GPBAR1CYP3A4PDE3ALMNA | |
| SCHEMBL13651506 | 0.89 | GPBAR1 (0.82) | NR1H4GPBAR1CYP3A4PDE3ALMNA | |
| SCHEMBL15156606 | 0.89 | GPBAR1 (0.82) | NR1H4GPBAR1CYP3A4PDE3ALMNA | |
| SCHEMBL13340036 | 0.89 | GPBAR1 (0.82) | NR1H4GPBAR1CYP3A4PDE3ALMNA | |
| SCHEMBL30555841 | 0.88 | NR1H4 (1.00) | NR1H4GPBAR1CYP3A4LMNAABCB11 | |
| SCHEMBL30555795 | 0.88 | NR1H4 (1.00) | NR1H4GPBAR1CYP3A4LMNAABCB11 | |
| SCHEMBL16227102 | 0.88 | GPBAR1 (0.70) | NR1H4GPBAR1CYP3A4PDE3ALMNA | |
| SCHEMBL9760162 | 0.86 | GPBAR1 (0.73) | NR1H4GPBAR1CYP3A4PDE3ALMNA | |
| SCHEMBL30892362 | 0.83 | GPBAR1 (0.76) | NR1H4GPBAR1CYP3A4PDE3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197341-A1 | CATHETER AND PROBE FOR MEASURING ANALYTES OR OTHER PARAMETERS | Edwards Lifesciences Corporation (US) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009021172-A1 | CATHETER AND PROBE FOR MEASURING ANALYTES OR OTHER PARAMETERS | EDWARDS LIFESCIENCES CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |