Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL28459202

CCCC[N+](CCCC)(CCCC)CCCC.O=S(=O)(O)CCCCS(=O)(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.55
SLC22A2 O15244 1/20 0.48
EPHX2 P34913 1/20 0.46
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
FAAH O00519 2/20 0.43
DNM1 Q05193 4/20 0.41
APP P05067 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35194 0.98 SLC22A1 (0.52) SLC22A1SLC22A2EPHX2ALDH1A1TP53
Tetrabuthylammonium SCHEMBL27850437 0.98 SLC22A1 (0.52) SLC22A1SLC22A2EPHX2ALDH1A1TP53
Tetrabuthylammonium SCHEMBL27771268 0.95 SLC22A1 (0.55) SLC22A1SLC22A2EPHX2ALDH1A1TP53
SCHEMBL15965937 0.95 SLC22A1 (0.55) SLC22A1SLC22A2EPHX2ALDH1A1TP53
Tetrabuthylammonium SCHEMBL28208963 0.94 SLC22A1 (0.48) SLC22A1SLC22A2EPHX2ALDH1A1TP53
SCHEMBL34983 0.94 SLC22A1 (0.48) SLC22A1SLC22A2EPHX2ALDH1A1TP53
Tetrabuthylammonium SCHEMBL28206434 0.93 SLC22A1 (0.52) SLC22A1SLC22A2EPHX2ALDH1A1TP53
SCHEMBL29506651 0.93 SLC22A1 (0.56) SLC22A1SLC22A2EPHX2ALDH1A1TP53
SCHEMBL10138705 0.93 SLC22A1 (0.56) SLC22A1SLC22A2EPHX2ALDH1A1TP53
Tetrahexylammonium SCHEMBL27789106 0.93 SLC22A1 (0.56) SLC22A1SLC22A2EPHX2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109276569-B Stable crystal form pharmaceutical composition and preparation method and application thereof 四川海思科制药有限公司 2020-09-29 CN disclosed