SCHEMBL28459607

SCHEMBL28459607

C#CCOP(=O)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA4 P22748 3/20 0.50
CA5A P35218 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA5B Q9Y2D0 3/20 0.50
SRC P12931 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
ELANE P08246 1/20 0.41
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.38
PKM P14618 1/20 0.37
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2639353 0.86 MEN1 (0.45) CA12CA1CA2CA4CA5A
SCHEMBL11362652 0.82 CA12 (0.48) CA12CA1CA2CA4CA5A
SCHEMBL27436329 0.82 SRC (0.50) CA12CA1CA2CA4CA5A
SCHEMBL11806136 0.81 CA12 (0.47) CA12CA1CA2CA4CA5A
SCHEMBL12728757 0.78 SRC (0.52) SRCL3MBTL1TDP1ELANEMEN1
SCHEMBL343402 0.78 SRC (0.52) CA2SRCL3MBTL1TDP1ELANE
SCHEMBL23037761 0.76 TSHR (0.52) CA12CA1CA2CA4CA5A
SCHEMBL28358861 0.76 SRC (0.50) SRCL3MBTL1TDP1ELANEMEN1
Triphenyl Phosphate SCHEMBL483692 0.75 SRC (0.64) SRCL3MBTL1TDP1MEN1HTT
Triphenyl Phosphate SCHEMBL18116 0.75 SRC (0.64) SRCL3MBTL1TDP1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111606945-B Preparation method of compound containing P-O bond or P-S bond 烟台大学 2023-06-20 CN disclosed
CN-111606945-A Preparation method of compound containing P-O bond or P-S bond 烟台大学 2020-09-01 CN disclosed