SCHEMBL28459677

SCHEMBL28459677

Cc1ccc(C=CC(=O)c2cc3ccccc3oc2=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.62
GAA P10253 2/20 0.61
MGAM O43451 1/20 0.61
SI P14410 1/20 0.61
MGAM2 Q2M2H8 1/20 0.61
CA9 Q16790 4/20 0.59
MAOA P21397 4/20 0.58
KDM4E B2RXH2 4/20 0.56
CA12 O43570 3/20 0.56
CYP1A2 P05177 2/20 0.56
NT5E P21589 1/20 0.56
CA1 P00915 1/20 0.54
CA3 P07451 1/20 0.54
TSHR P16473 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
GPR35 Q9HC97 1/20 0.54
CA14 Q9ULX7 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28459676 1.00 MAOB (0.62) MAOBGAAMGAMSIMGAM2
SCHEMBL28244685 0.89 MAOB (0.68) MAOBGAAMGAMSIMGAM2
SCHEMBL28244683 0.89 MAOB (0.68) MAOBGAAMGAMSIMGAM2
SCHEMBL30214859 0.88 MAOB (0.64) MAOBGAACA9MAOAKDM4E
SCHEMBL28245360 0.88 MAOB (0.64) MAOBGAACA9MAOAKDM4E
SCHEMBL28245357 0.88 MAOB (0.64) MAOBGAACA9MAOAKDM4E
SCHEMBL28461843 0.87 MAOB (0.62) MAOBGAAMGAMSIMGAM2
SCHEMBL28470322 0.87 MAOB (0.70) MAOBCA9MAOAKDM4ECA12
SCHEMBL28459640 0.87 MAOB (0.62) MAOBCA9MAOAKDM4ECA12
SCHEMBL28461844 0.87 MAOB (0.62) MAOBGAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111588718-B Alpha-glucosidase inhibitor and application thereof 五邑大学 2021-06-08 CN disclosed
CN-111588718-A Alpha-glucosidase inhibitor and application thereof 五邑大学 2020-08-28 CN disclosed