Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17141089 | 0.85 | MEN1 (0.46) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL18337645 | 0.83 | MEN1 (0.45) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL843323 | 0.82 | TDP1 (0.48) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL12698678 | 0.82 | TDP1 (0.48) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL4202727 | 0.82 | TDP1 (0.48) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL1444341 | 0.80 | MEN1 (0.49) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL14776705 | 0.80 | MEN1 (0.49) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL3229252 | 0.78 | TDP1 (0.46) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL28760650 | 0.78 | TDP1 (0.50) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL16295315 | 0.78 | MEN1 (0.47) | MEN1GAAKMT2ATDP1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215787-A | Somatostatin receptor 5 antagonists and uses thereof | 中国科学院上海药物研究所 | 2022-10-21 | — | — | CN | disclosed |
| CN-109790145-B | Dihydropyrimidine compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-09-22 | — | — | CN | disclosed |