Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456300 | 0.91 | BTK (0.55) | BTK | |
| SCHEMBL28459013 | 0.91 | BTK (0.60) | BTKEGFR | |
| SCHEMBL28456041 | 0.91 | BTK (0.59) | BTKEGFR | |
| SCHEMBL28452608 | 0.89 | BTK (0.63) | BTK | |
| SCHEMBL28456245 | 0.89 | BTK (0.61) | BTK | |
| SCHEMBL28456027 | 0.87 | BTK (0.54) | BTKEGFR | |
| SCHEMBL29968858 | 0.87 | BTK (0.58) | BTKEGFR | |
| SCHEMBL29969258 | 0.87 | BTK (0.59) | BTK | |
| SCHEMBL28457701 | 0.87 | BTK (0.58) | BTKEGFR | |
| SCHEMBL28455479 | 0.87 | BTK (0.59) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662232-B | Small molecule compound with 2H-indazole structure and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-08-02 | — | — | CN | disclosed |
| CN-111662232-A | Small molecule compound with 2H-indazole structure and synthesis and application thereof | 中国科学院上海药物研究所 | 2020-09-15 | — | — | CN | disclosed |