Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459135 | 0.90 | MAPT (0.46) | LMNAL3MBTL1MAPTIDO1TP53 | |
| SCHEMBL28470725 | 0.72 | NPSR1 (0.40) | L3MBTL1MAPTIDO1TP53GLA | |
| SCHEMBL8932766 | 0.65 | IDO1 (0.60) | L3MBTL1MAPTIDO1TP53GLA | |
| SCHEMBL29764730 | 0.65 | IDO1 (0.60) | L3MBTL1MAPTIDO1TP53GLA | |
| SCHEMBL29727842 | 0.65 | MAPT (0.45) | LMNAL3MBTL1MAPTIDO1TP53 | |
| SCHEMBL26794064 | 0.65 | MAPT (0.45) | LMNAL3MBTL1MAPTIDO1TP53 | |
| SCHEMBL23431476 | 0.65 | KMT2A (0.54) | LMNAL3MBTL1MAPTIDO1TP53 | |
| SCHEMBL8289554 | 0.63 | GAA (0.75) | LMNAL3MBTL1MAPTIDO1TP53 | |
| SCHEMBL29456688 | 0.63 | GAA (0.75) | LMNAL3MBTL1MAPTIDO1TP53 | |
| SCHEMBL10481528 | 0.62 | MEN1 (0.57) | MAPTCYP3A4HSD17B10KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333614-B | Quinolinone compounds and use thereof | 遵义医科大学珠海校区 | 2021-01-15 | — | — | CN | claimed |
| CN-111333614-A | Quinolinone compounds and use thereof | 遵义医科大学珠海校区 | 2020-06-26 | — | — | CN | claimed |
| CN-111333614-B | Quinolinone compounds and use thereof | 遵义医科大学珠海校区 | 2021-01-15 | — | — | CN | disclosed |
| CN-111333614-A | Quinolinone compounds and use thereof | 遵义医科大学珠海校区 | 2020-06-26 | — | — | CN | disclosed |