Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 8/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23431086 | 0.91 | SLCO1B1 (0.54) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL29612876 | 0.91 | SLCO1B1 (0.54) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL23404134 | 0.86 | SLCO1B1 (0.73) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL23404133 | 0.86 | SLCO1B1 (0.73) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL28457503 | 0.86 | SLCO1B1 (0.73) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL21058139 | 0.85 | SLCO1B1 (0.72) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL31374532 | 0.82 | SLCO1B1 (0.61) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL21098000 | 0.82 | SLCO1B1 (0.61) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL23404168 | 0.82 | SLCO1B1 (0.63) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL23404170 | 0.82 | SLCO1B1 (0.63) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712492-A | Cyclohexaneacetic acid triazolazoles as LPA antagonists | 百时美施贵宝公司 | 2020-09-25 | — | — | CN | disclosed |