SCHEMBL28463594

SCHEMBL28463594

CC(C)(C)OC(=O)NCCc1ccc(OCC2CC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.49
CA1 P00915 6/20 0.47
CA2 P00918 6/20 0.47
ACACB O00763 4/20 0.47
CA12 O43570 5/20 0.47
CA9 Q16790 5/20 0.47
PARP15 Q460N3 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PARP2 Q9UGN5 1/20 0.45
GLA P06280 1/20 0.44
KMT2A Q03164 1/20 0.44
MTNR1A P48039 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23291164 0.91 NAMPT (0.49) NAMPTCA1CA2CA12CA9
SCHEMBL1295105 0.83 ACACB (0.45) CA1CA2ACACBCA12CA9
SCHEMBL27741033 0.83 ACACB (0.59) NAMPTCA1CA2ACACBCA12
SCHEMBL5892281 0.82 CA1 (0.55) NAMPTCA1CA2ACACBCA12
SCHEMBL1541945 0.82 CA1 (0.64) NAMPTCA1CA2ACACBCA12
SCHEMBL26964370 0.81 CA1 (0.56) NAMPTCA1CA2ACACBCA12
SCHEMBL4427701 0.81 PTPN1 (0.52) NAMPTCA1CA2CA12CA9
SCHEMBL19003451 0.81 ACACB (0.61) NAMPTCA1CA2ACACBCA12
SCHEMBL2187363 0.81 CA1 (0.50) NAMPTCA1CA2ACACBCA12
SCHEMBL8757522 0.80 GLA (0.67) NAMPTCA1CA2GLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111747944-B Broad-spectrum anti-enveloped virus compound, composition and application thereof 复旦大学 2022-09-30 CN disclosed
CN-111747944-A Broad-spectrum anti-enveloped virus compound, composition and application thereof 复旦大学 2020-10-09 CN disclosed