SCHEMBL28465160

SCHEMBL28465160

O=C(O)Oc1ccccc1-c1ccccc1NC(=O)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.50
KMT2A Q03164 6/20 0.48
MEN1 O00255 3/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ALDH1A1 P00352 9/20 0.46
CYP1A2 P05177 3/20 0.46
MAPT P10636 4/20 0.45
KDM4E B2RXH2 5/20 0.45
HPGD P15428 2/20 0.45
RAD51 Q06609 1/20 0.44
GAA P10253 4/20 0.44
GLA P06280 1/20 0.44
ATM Q13315 1/20 0.44
MAOB P27338 1/20 0.44
THRB P10828 1/20 0.42
GFER P55789 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6488638 0.87 KMT2A (0.55) TRPV1KMT2AMEN1NPC1RAB9A
SCHEMBL28469354 0.86 KMT2A (0.44) TRPV1KMT2AALDH1A1CYP1A2MAPT
SCHEMBL28471143 0.82 MAPT (0.44) TRPV1KMT2AMEN1NPC1RAB9A
SCHEMBL28335754 0.81 MEN1 (0.60) TRPV1KMT2AMEN1NPC1RAB9A
SCHEMBL28474509 0.78 KMT2A (0.44) TRPV1KMT2AMEN1NPC1RAB9A
SCHEMBL7017642 0.78 FABP3 (0.44) KMT2AALDH1A1CYP1A2MAPTKDM4E
SCHEMBL9561938 0.77 TRPV1 (0.49) TRPV1KMT2AMEN1NPC1RAB9A
SCHEMBL11176848 0.76 KMT2A (0.72) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL4860352 0.75 CTNNB1 (0.50) KMT2AGAAHTTSMN1; SMN2LMNA
SCHEMBL1641651 0.74 KMT2A (0.55) TRPV1KMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108517022-B Solid catalyst component for olefin polymerization, catalyst and application thereof 北京利和知信科技有限公司 2020-10-27 CN disclosed
CN-108517021-B Solid catalyst component suitable for producing polymer with wide molecular weight distribution, catalyst and application thereof 北京利和知信科技有限公司 2020-10-27 CN disclosed