Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11774235 | 0.75 | TDP1 (0.56) | TDP1MCL1KDM4EALDH1A1HPGD | |
| SCHEMBL2517136 | 0.73 | TDP1 (0.57) | TDP1MCL1KDM4EALDH1A1HPGD | |
| SCHEMBL132481 | 0.73 | TDP1 (0.62) | TDP1MCL1KDM4EALDH1A1HPGD | |
| SCHEMBL6490027 | 0.73 | TDP1 (0.57) | TDP1MCL1KDM4EALDH1A1HPGD | |
| SCHEMBL8600070 | 0.73 | TDP1 (0.57) | TDP1MCL1KDM4EALDH1A1HPGD | |
| SCHEMBL4703042 | 0.73 | TDP1 (0.57) | TDP1MCL1KDM4EALDH1A1HPGD | |
| SCHEMBL7466689 | 0.72 | TDP1 (0.53) | TDP1MCL1KDM4EALDH1A1HPGD | |
| SCHEMBL3700016 | 0.72 | TDP1 (0.53) | TDP1MCL1KDM4EALDH1A1HPGD | |
| SCHEMBL31598898 | 0.70 | PTPN1 (0.58) | TDP1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL2242814 | 0.70 | PTPN1 (0.58) | TDP1KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825716-B | Naphthoxazole phosphine oxide compound, synthesis method thereof and catalytic application of naphthoxazole phosphine oxide compound as ligand | 湖南大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-111825716-A | Naphthoxazole phosphine oxide compound, synthesis method thereof and catalytic application of naphthoxazole phosphine oxide compound as ligand | 湖南大学 | 2020-10-27 | — | — | CN | disclosed |