SCHEMBL284668

SCHEMBL284668

CCCCC(CC)COC(=O)Cc1cc(C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
TSHR P16473 3/20 0.47
ATM Q13315 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
ALDH1A1 P00352 5/20 0.43
CA2 P00918 1/20 0.43
LMNA P02545 3/20 0.42
MAPK1 P28482 3/20 0.42
RECQL P46063 1/20 0.41
GAA P10253 3/20 0.40
XBP1 P17861 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HSD17B10 Q99714 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
BCL2L1 Q07817 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283905 0.93 CYP3A4 (0.51) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL284594 0.89 CYP3A4 (0.51) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL284444 0.82 CYP3A4 (0.56) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL14438470 0.82 ATM (0.41) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL14438471 0.81 GAA (0.42) CYP3A4TSHRATMTDP1ALDH1A1
SCHEMBL284341 0.80 ESR1 (0.51) ALDH1A1HSD17B10ESR1
SCHEMBL284042 0.80 ESR1 (0.51) ALDH1A1HSD17B10ESR1
SCHEMBL283613 0.80 ESR1 (0.51) ALDH1A1HSD17B10ESR1
SCHEMBL284402 0.80 ESR1 (0.51) ALDH1A1HSD17B10ESR1
SCHEMBL283992 0.80 ESR1 (0.51) ALDH1A1HSD17B10ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2428553-B1 Lubricating oil composition NIPPON OIL CORP (JP) 2013-05-22 EP disclosed
US-8299006-B2 Compressor oil composition NIPPON OIL CORPORATION (JP) 2012-10-30 US disclosed
US-8247360-B2 Heat treating oil composition NIPPON OIL CORPORATION (JP) 2012-08-21 US disclosed
US-8236740-B2 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2012-08-07 US disclosed
US-8232233-B2 Lubricating oil composition for machine tools NIPPON OIL CORPORATION (JP) 2012-07-31 US disclosed
US-8227387-B2 Metalworking oil composition NIPPON OIL CORPORATION (JP) 2012-07-24 US disclosed
US-8227388-B2 Hydraulic oil composition NIPPON OIL CORPORATION (JP) 2012-07-24 US disclosed
US-8193129-B2 Refrigerator oil, compressor oil composition, hydraulic fluid composition, metalworking fluid composition, heat treatment oil composition, lubricant composition for machine tool and lubricant composition NIPPON OIL CORPORATION (JP) 2012-06-05 US disclosed
EP-2428555-A1 Metalworking oil composition Nippon Oil Corporation (JP) 2012-03-14 EP disclosed
EP-2428553-A1 Lubricating oil composition Nippon Oil Corporation (JP) 2012-03-14 EP disclosed
US-20120053097-A1 Metal working oil composition NIPPON OIL CORPORATION 2012-03-01 US disclosed
US-20120053096-A1 Lubricating oil composition for machine tools NIPPON OIL CORPORATION 2012-03-01 US disclosed
US-20120053375-A1 Heat treating oil composition NIPPON OIL CORPORATION 2012-03-01 US disclosed
US-20120053094-A1 Hydraulic oil composition NIPPON OIL CORPORATION 2012-03-01 US disclosed
EP-2423298-A1 Compressor oil composition Nippon Oil Corporation (JP) 2012-02-29 EP disclosed
EP-2423297-A1 Hydraulic oil composition Nippon Oil Corporation (JP) 2012-02-29 EP disclosed
EP-2423296-A1 Lubricating oil composition for machine tools Nippon Oil Corporation (JP) 2012-02-29 EP disclosed
US-20120046205-A1 Compressor oil composition NIPPON OIL CORPORATION 2012-02-23 US disclosed
US-20100093568-A1 REFRIGERATOR OIL, COMPRESSOR OIL COMPOSITION, HYDRAULIC FLUID COMPOSITION, METALWORKING FLUID COMPOSITION, HEAT TREATMENT OIL COMPOSITION, LUBRICANT COMPOSITION FOR MACHINE TOOL AND LUBRICANT COMPOSITION NIPPON OIL CORPORATION (JP) 2010-04-15 US disclosed
EP-2039746-A1 REFRIGERATOR OIL, COMPRESSOR OIL COMPOSITION, HYDRAULIC FLUID COMPOSITION, METALWORKING FLUID COMPOSITION, HEAT TREATMENT OIL COMPOSITION, LUBRICANT COMPOSITION FOR MACHINE TOOL AND LUBRICANT COMPOSITION Nippon Oil Corporation (JP) 2009-03-25 EP disclosed