Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462539 | 0.90 | PARP10 (0.46) | LMNAHRH3PRSS1L3MBTL1 | |
| SCHEMBL10710138 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 | |
| SCHEMBL16902874 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 | |
| SCHEMBL16902872 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 | |
| SCHEMBL16902868 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 | |
| SCHEMBL16902883 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 | |
| SCHEMBL8369936 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 | |
| SCHEMBL16902880 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 | |
| SCHEMBL16902866 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 | |
| SCHEMBL16902867 | 0.84 | HRH3 (0.58) | LMNAPRMT1F2ST14HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321472-A | Novel monothiol mucolytic agents | 帕里昂科学公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-107614480-B | Novel monothiol mucolytic agents | 帕里昂科学公司 | 2020-09-15 | — | — | CN | disclosed |