Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.76 |
| ▸ | BTK | Q06187 | 11/20 | 0.76 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30091817 | 1.00 | EGFR (0.76) | EGFRBTKUSP30IGF1RPIK3CD | |
| SCHEMBL22400925 | 0.95 | EGFR (0.75) | EGFRBTKUSP30RIPK2 | |
| SCHEMBL22400982 | 0.88 | EGFR (0.83) | EGFRBTK | |
| SCHEMBL30091818 | 0.86 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL22400922 | 0.86 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL22405025 | 0.85 | BTK (0.76) | EGFRBTKUSP30RIPK2 | |
| SCHEMBL22431577 | 0.85 | EGFR (0.74) | EGFRBTKUSP30IGF1R | |
| SCHEMBL22405035 | 0.84 | BTK (0.73) | EGFRBTKUSP30RIPK2 | |
| SCHEMBL22400898 | 0.83 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL30313820 | 0.83 | EGFR (1.00) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278818-B | BTK inhibitor compounds | 伊莱利利公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-111278818-A | BTK inhibitor compounds | 伊莱利利公司 | 2020-06-12 | — | — | CN | disclosed |