Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.52 |
| ▸ | TUBB | P07437 | 2/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467186 | 1.00 | KMT2A (0.73) | KMT2ALMNAMAPTKDM4EMEN1 | |
| SCHEMBL28462780 | 1.00 | KMT2A (0.73) | KMT2ALMNAMAPTKDM4EMEN1 | |
| SCHEMBL28462778 | 0.94 | KMT2A (0.82) | KMT2ALMNAMAPTKDM4EMEN1 | |
| SCHEMBL3687875 | 0.90 | KMT2A (0.75) | KMT2ALMNAMAPTKDM4EMEN1 | |
| SCHEMBL3683227 | 0.90 | KMT2A (0.75) | KMT2ALMNAMAPTKDM4EMEN1 | |
| SCHEMBL16797095 | 0.88 | FFAR1 (0.63) | KMT2ALMNAMAPTKDM4EMEN1 | |
| SCHEMBL16797096 | 0.88 | FFAR1 (0.63) | KMT2ALMNAMAPTKDM4EMEN1 | |
| Triacetylresveratrol SCHEMBL717980 | 0.85 | TTR (1.00) | KMT2ALMNAMAPTKDM4EMEN1 | |
| Triacetylresveratrol SCHEMBL717979 | 0.85 | TTR (1.00) | KMT2ALMNAMAPTKDM4EMEN1 | |
| SCHEMBL20786804 | 0.85 | TTR (0.79) | KMT2ALMNAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777577-A | Taxol derivative and application thereof in preparation of medicine for preventing and treating human malignant tumor | 天津仁雨生物科技有限公司 | 2020-10-16 | — | — | CN | disclosed |