SCHEMBL284676

SCHEMBL284676

O=[N+]([O-])c1ccc(O[C@H]2[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)O[C@@H]3CO)O[C@H](CO)[C@@H](O)[C@@H]2O)cc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
NFKB1 P19838 1/20 0.47
THPO P40225 1/20 0.47
ALDH1A1 P00352 1/20 0.47
PMP22 Q01453 1/20 0.47
TYR P14679 3/20 0.47
HPSE Q9Y251 1/20 0.45
AMY2A P04746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6514488 1.00 CYP1A2 (0.47) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL9806246 0.98 TYR (0.48) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL6873455 0.93 CYP1A2 (0.46) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL8313911 0.92 CYP1A2 (0.47) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL5831825 0.92 CYP1A2 (0.47) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL8315726 0.92 CYP1A2 (0.47) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL9563939 0.92 CYP1A2 (0.47) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL7958087 0.90 TYR (0.57) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL5831830 0.90 TYR (0.57) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL10653843 0.90 TYR (0.57) CYP1A2NFKB1THPOALDH1A1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2428578-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME National University Corporation Kagoshima University (JP) 2012-03-14 EP claimed
EP-2636749-B1 NON-REDUCING END-MODIFIED GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF EZAKI GLICO CO (JP) 2016-08-03 EP disclosed
EP-2428578-B1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME EZAKI GLICO CO (JP) 2016-03-23 EP disclosed
US-20130302405-A1 AMINO SUGAR-CONTAINING GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF EZAKI GLICO CO., LTD. (JP) 2013-11-14 US disclosed
US-20130295163-A1 NON-REDUCING END MODIFIED GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF EZAKI GLICO CO., LTD. (JP) 2013-11-07 US disclosed
US-8575131-B2 Glucuronic acid-containing glucan, process for production of same, and use of same NATIONAL UNIVERSITY CORPORATION KAGOSHIMA UNIVERSITY (JP) 2013-11-05 US disclosed
EP-2636749-A1 NON-REDUCING END-MODIFIED GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF Ezaki Glico Co., Ltd. (JP) 2013-09-11 EP disclosed
EP-2636748-A1 AMINO SUGAR-CONTAINING GLUCAN, METHOD FOR PRODUCING SAME AND USE OF SAME Ezaki Glico Co., Ltd. (JP) 2013-09-11 EP disclosed
US-20120135063-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME EZAKI GLICO CO., LTD. (JP) 2012-05-31 US disclosed
EP-2428578-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME National University Corporation Kagoshima University (JP) 2012-03-14 EP disclosed
US-20060236426-A1 Nucleic acid molecules encoding starch degrading enzymes MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2006-10-19 US disclosed
EP-1381676-A2 NUCLEIC ACID MOLECULES ENCODING STARCH DEGRADING ENZYMES MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) 2004-01-21 EP disclosed
US-20030175843-A1 Reagent, method and apparatus for measuring amylase activity TOYAMA UNIVERSITY (JP) 2003-09-18 US disclosed
US-20030175842-A1 Kit which uses maltose and chromogens to quantify hydrolase activity and diagnose pancreatic, kidney, liver or tumor disorders TOYAMA UNIVERSITY (JP) 2003-09-18 US disclosed
EP-1342790-A2 Reagent and method for measuring amylase activity Toyama University (JP) 2003-09-10 EP disclosed
EP-1342791-A2 Reagent, method and apparatus for measuring amylase activity Toyama University (JP) 2003-09-10 EP disclosed
US-20030135878-A1 Transgenic plants with elevated thioredoxin levels REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2003-07-17 US disclosed
WO-2002086112-A2 NUCLEIC ACID MOLECULES ENCODING STARCH DEGRADING ENZYMES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2002-10-31 WO disclosed
EP-0173255-B1 OLIGOSACCHARIDE DERIVATIVES AND THEIR USE AS SUBSTRATE FOR MEASURING ALPHA-AMYLASE ACTIVITY WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1991-04-17 EP disclosed
US-4683198-A DOES NOT REQUIRE NAD OR NADP TOYO JOZO KABUSHIKI KAISHA (JP) 1987-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130302405-A1 AMINO SUGAR-CONTAINING GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF GALE, MGAM, ENGASE CYP1A2 3606/4885NFKB1 1440/4885THPO 2553/4885
US-20120135063-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME ENGASE, FUCA1, ALG8 CYP1A2 1744/4885NFKB1 1375/4885THPO 3214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.