Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586064 | 1.00 | NPSR1 (0.43) | NPSR1GLO1ALDH1A1TSHRLMNA | |
| SCHEMBL7586059 | 1.00 | NPSR1 (0.43) | NPSR1GLO1ALDH1A1TSHRLMNA | |
| SCHEMBL8013677 | 0.81 | — | — | |
| SCHEMBL43053 | 0.81 | — | — | |
| SCHEMBL43052 | 0.81 | — | — | |
| SCHEMBL149362 | 0.79 | TSHR (0.52) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8509099 | 0.79 | TSHR (0.50) | NPSR1ALDH1A1TSHRLMNACYP2D6 | |
| SCHEMBL41974 | 0.79 | TSHR (0.52) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7190576 | 0.79 | TSHR (0.52) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13269641 | 0.76 | NPSR1 (0.58) | NPSR1GLO1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295373-A | Compositions and methods for treating brain injury | 阿泽凡药物公司 | 2020-06-16 | — | — | CN | disclosed |