Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17949431 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL1459707 | 0.75 | KMT2A (0.45) | HSD17B10KDM4EALDH1A1KMT2A | |
| SCHEMBL9197048 | 0.73 | — | — | |
| SCHEMBL9543630 | 0.72 | GAA (0.43) | SMN1; SMN2TSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL2998525 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRCYP1A2ALPLKDM4E | |
| SCHEMBL27463853 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP1A2KDM4EALDH1A1POLB | |
| SCHEMBL3416368 | 0.69 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRKDM4EPOLBMEN1 | |
| SCHEMBL27682646 | 0.69 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP1A2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL10715626 | 0.68 | KDM1A (0.37) | SMN1; SMN2TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL3230585 | 0.68 | SMN1; SMN2 (0.34) | SMN1; SMN2CYP1A2ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808024-B | Phenyl pyrazolone compound or salt thereof, preparation method and application | 郑州手性药物研究院有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-111808024-A | Phenylpyrazolone compound or salt thereof, preparation method and application | 郑州手性药物研究院有限公司 | 2020-10-23 | — | — | CN | disclosed |