Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 19/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464879 | 0.90 | TNIK (0.71) | TNIK | |
| SCHEMBL28477806 | 0.90 | TNIK (0.67) | TNIK | |
| SCHEMBL28476055 | 0.90 | TNIK (0.69) | TNIK | |
| SCHEMBL28900134 | 0.89 | TNIK (0.65) | TNIK | |
| SCHEMBL22978341 | 0.87 | TNIK (0.67) | TNIK | |
| SCHEMBL31203810 | 0.87 | TNIK (0.67) | TNIK | |
| SCHEMBL22978330 | 0.87 | TNIK (0.67) | TNIK | |
| SCHEMBL22978342 | 0.86 | TNIK (0.70) | TNIK | |
| SCHEMBL22978359 | 0.84 | TNIK (0.69) | TNIK | |
| SCHEMBL28474354 | 0.83 | TNIK (0.69) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836801-B | Compounds for inhibiting TNIK and medical use thereof | 韩国化学硏究院 | 2024-02-02 | — | — | CN | claimed |
| CN-111836801-A | Compound for inhibiting TNIK and medical application thereof | 韩国化学硏究院 | 2020-10-27 | — | — | CN | claimed |