Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.70 |
| ▸ | IGF1R | P08069 | 3/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.69 |
| ▸ | INSR | P06213 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942095 | 1.00 | EGFR (0.70) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28471883 | 0.95 | EGFR (0.70) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28942033 | 0.95 | EGFR (0.70) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL14719238 | 0.93 | EGFR (0.80) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28963872 | 0.90 | EGFR (0.87) | EGFRIGF1RKCNH2 | |
| SCHEMBL28463739 | 0.90 | EGFR (0.87) | EGFRIGF1RKCNH2 | |
| SCHEMBL28469668 | 0.89 | EGFR (0.88) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28942072 | 0.89 | EGFR (0.88) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL14719111 | 0.88 | EGFR (0.79) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28942081 | 0.87 | EGFR (0.73) | EGFRIGF1RKCNH2INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191861-B | N- [5- (pyrimidin-2-amino) -2, 4-disubstituted-phenyl ] -trans-2, 4-pentadiene-amide | 天津大学 | 2020-10-02 | — | — | CN | disclosed |