Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31576767 | 1.00 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL20477520 | 0.86 | — | — | |
| SCHEMBL8740795 | 0.83 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL8527487 | 0.80 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL27470057 | 0.78 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL534732 | 0.77 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL27498971 | 0.77 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL22638678 | 0.77 | MEN1 (0.58) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL28469271 | 0.77 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL8529398 | 0.75 | MEN1 (0.45) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3366669-B1 | MONOSUBSTITUTED OR POLYSUBSTITUTED AMPHIPHILIC HYPOCRELLIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND USES THEREOF | TECHNICAL INST OF PHYSICS AND CHEMISTRY OF THE CHINESE ACADEMY OF SCIENCES (CN) | 2025-05-21 | — | — | EP | disclosed |
| CN-111825624-B | Ester-water amphiphilic hypocrellin derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2021-07-27 | — | — | CN | disclosed |
| CN-107935943-B | Ester-water amphiphilic hypocrellin derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2021-06-29 | — | — | CN | disclosed |
| CN-111825624-A | Ester-water amphiphilic hypocrellin derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2020-10-27 | — | — | CN | disclosed |