⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18702975 | 0.97 | — | — | |
| SCHEMBL8695198 | 0.97 | LCK (0.48) | — | |
| SCHEMBL29696889 | 0.97 | LCK (0.48) | — | |
| SCHEMBL7574190 | 0.97 | LCK (0.48) | — | |
| SCHEMBL542069 | 0.91 | — | — | |
| SCHEMBL5953804 | 0.84 | HSD17B10 (0.39) | — | |
| SCHEMBL5954068 | 0.81 | HSD17B10 (0.36) | — | |
| SCHEMBL542053 | 0.78 | — | — | |
| SCHEMBL9775358 | 0.77 | — | — | |
| SCHEMBL834151 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677815-B | PROTAC compound for targeted degradation of PTP1B and preparation method and application thereof | 江西中医药大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-115677815-A | PROTAC compound for targeted degradation of PTP1B and preparation method and application thereof | 江西中医药大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-113075346-A | Gas chromatography separation analysis method based on aromatic macrocycle, molecular cage and pillar quinone and application | 天津师范大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111246855-A | Compounds and methods for transmembrane delivery of molecules | 艾博森斯有限公司 | 2020-06-05 | — | — | CN | disclosed |
| EP-3648773-A1 | COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES | Aposense Ltd. (IL) | 2020-05-13 | — | — | EP | disclosed |
| US-10195286-B2 | Compounds and methods for trans-membrane delivery of molecules | APOSENSE LTD. (IL) | 2019-02-05 | — | — | US | disclosed |
| WO-2019008574-A1 | COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES | APOSENSE LTD. (IL) | 2019-01-10 | — | — | WO | disclosed |
| US-20190008976-A1 | COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES | APOSENSE LTD. (IL) | 2019-01-10 | — | — | US | disclosed |
| CN-104177289-B | Chlorine hexyloxyethoxy ethyl compound and its pharmaceutical composition and purposes | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-10-27 | — | — | CN | disclosed |
| CN-104177289-A | Chloro-hexyloxy-ethyoxyl-ethyl compound, and pharmaceutical composition and application thereof | INST PHARM & TOXICOLOGY AMMS | 2014-12-03 | — | — | CN | disclosed |
| EP-0551867-B1 | Laminated transparent plastic material and polymerizable monomer | MITSUI CHEMICALS INC (JP) | 2000-06-07 | — | — | EP | disclosed |
| CN-1247535-A | Aminoepoxides from aminoaldehydes and in-situ formed halomethyl organometallic reagent | SEARLE & CO (US) | 2000-03-15 | — | — | CN | disclosed |
| US-5916983-A | Biologically active compounds by catalytic olefin metathesis | BEND RESEARCH, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5659084-A | LEUKOTRIENE ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| US-5451695-A | Acrylic ester monomer with carbamate group, glazing for windows | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-09-19 | — | — | US | disclosed |
| EP-0643682-A4 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 2-SUBSTITUTED BENZALDEHYDES. | SMITHKLINE BEECHAM CORP (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0643682-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 2-SUBSTITUTED BENZALDEHYDES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5393607-A | Glazing materials; hardness, impact strength, scratch resistance | MITSUI TOATSU CHEMICLAS, INC. (JP) | 1995-02-28 | — | — | US | disclosed |
| WO-1993019033-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 2-SUBSTITUTED BENZALDEHYDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-30 | — | — | WO | disclosed |
| EP-0551867-A1 | Laminated transparent plastic material and polymerizable monomer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-07-21 | — | — | EP | disclosed |