Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 17/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899145 | 0.92 | PIK3CB (0.43) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG | |
| SCHEMBL28899143 | 0.92 | PIK3CB (0.45) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG | |
| SCHEMBL28466042 | 0.91 | PIK3CB (0.42) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG | |
| SCHEMBL28468496 | 0.91 | PIK3CB (0.42) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG | |
| SCHEMBL28459214 | 0.91 | PIK3CB (0.44) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG | |
| SCHEMBL28471861 | 0.90 | PIK3CB (0.44) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG | |
| SCHEMBL28900047 | 0.90 | PIK3CB (0.42) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG | |
| SCHEMBL28465744 | 0.88 | PIK3CB (0.42) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL28465987 | 0.86 | PIK3CB (0.43) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG | |
| SCHEMBL12802393 | 0.85 | PIK3CB (0.62) | PIK3CBPIK3CDPIK3CAPIK3R1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501241-B | Compounds, pharmaceutical compositions containing them and their use in the treatment of proliferative diseases | 梅制药公司 | 2020-10-13 | — | — | CN | disclosed |