Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31757289 | 0.88 | GRIN1 (0.54) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL31757256 | 0.85 | GRIN1 (0.64) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL29088828 | 0.85 | GRIN1 (0.63) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL29088774 | 0.85 | GRIN1 (0.63) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL29088777 | 0.84 | GRIN1 (0.55) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL29515670 | 0.81 | GRIN1 (0.64) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL21487993 | 0.81 | GRIN1 (0.64) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL21488779 | 0.81 | GRIN1 (0.64) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL28474229 | 0.81 | GRIN1 (0.64) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL25889589 | 0.81 | GRIN1 (0.58) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4681777-A2 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XWPharma Ltd. (KY) | 2026-01-21 | — | — | EP | disclosed |
| EP-3737665-B1 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XWPHARMA LTD (KY) | 2026-01-07 | — | — | EP | disclosed |
| CN-114805139-A | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-111836798-B | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-111836798-A | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2020-10-27 | — | — | CN | disclosed |