Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.44 |
| ▸ | PPARA | Q07869 | 17/20 | 0.44 |
| ▸ | PPARG | P37231 | 12/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470899 | 1.00 | PPARD (0.44) | PPARDPPARAPPARGNPC1RECQL | |
| SCHEMBL29092331 | 1.00 | PPARD (0.44) | PPARDPPARAPPARGNPC1RECQL | |
| SCHEMBL29092710 | 0.92 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL29092310 | 0.92 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL29092312 | 0.92 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL29092699 | 0.90 | PPARD (0.36) | PPARDPPARAPPARG | |
| SCHEMBL29092700 | 0.90 | PPARD (0.36) | PPARDPPARAPPARG | |
| SCHEMBL29981161 | 0.90 | EGFR (0.38) | PPARDPPARAPPARG | |
| SCHEMBL29092703 | 0.90 | PPARD (0.36) | PPARDPPARAPPARG | |
| SCHEMBL28476519 | 0.90 | EGFR (0.38) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886227-B | Novel aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions containing them | 柳韩洋行 | 2023-10-13 | — | — | CN | disclosed |
| CN-111886227-A | Novel aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions containing them | 柳韩洋行 | 2020-11-03 | — | — | CN | disclosed |