SCHEMBL2847397

SCHEMBL2847397

CCC[C@H](N)CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1335718 1.00
SCHEMBL12050136 1.00
Hydrochloric Acid SCHEMBL22322358 0.97
Hydrochloric Acid SCHEMBL22322360 0.97
SCHEMBL364981 0.84
SCHEMBL284709 0.84
SCHEMBL854950 0.83
SCHEMBL8259926 0.83
SCHEMBL18109382 0.83
SCHEMBL854949 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12485123-B2 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2025-12-02 US disclosed
US-12440560-B2 Substituted pyrimidines as vaccine adjuvants Sumitomo Pharma Co., Ltd. (JP) 2025-10-14 US disclosed
EP-3603619-B1 VACCINE ADJUVANT FORMULATION SUMITOMO PHARMA CO LTD (JP) 2025-08-13 EP disclosed
US-20250059183-A1 PYRIDINE[4,3-D]PYRIMIDINE COMPOUND AS TLR7/8 AGONIST SHANGHAI VISONPHARMA CO., LTD. (CN) 2025-02-20 US disclosed
EP-4446323-A1 PYRIDINE[4,3-D]PYRIMIDINE COMPOUND AS TLR7/8 AGONIST Shanghai Visonpharma Co., Ltd. (CN) 2024-10-16 EP disclosed
US-12077510-B2 Carboxylic acid compounds Sumitomo Pharma Co., Ltd. (JP) 2024-09-03 US disclosed
CN-110650729-B Vaccine adjuvant formulations 住友制药株式会社 2024-08-20 CN disclosed
US-20240245766-A1 PYRIMIDINE COMPOUND Sumitomo Pharma Co., Ltd. (JP) 2024-07-25 US disclosed
CN-118382625-A Pyridine [4,3-d ] pyrimidines as TLR7/8 agonists 上海维申医药有限公司 2024-07-23 CN disclosed
CN-115135655-B 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists 百时美施贵宝公司 2024-07-02 CN disclosed
EP-2640716-A1 CYCLIC AMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2013-09-25 EP disclosed
US-20130045955-A1 NOVEL COMPOUNDS BENNETT NICHOLAS J (GB) 2013-02-21 US disclosed
EP-2222648-B1 PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS ASTRAZENECA AB (SE) 2013-01-09 EP disclosed
WO-2012156498-A1 QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES JANSSEN R&D IRELAND (IE) 2012-11-22 WO disclosed
US-8268990-B2 Compounds ASTRAZENECA AB (SE) 2012-09-18 US disclosed
WO-2012067268-A1 CYCLIC AMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2012-05-24 WO disclosed
WO-2012066336-A1 BENZYLAMINE COMPOUNDS AS TOLL -LIKE RECEPTOR 7 AGONISTS ASTRAZENECA AB (SE) 2012-05-24 WO disclosed
EP-2222648-A1 PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS AstraZeneca AB (SE) 2010-09-01 EP disclosed
US-20090209524-A1 Novel Compounds ASTRAZENECA AB (SE) 2009-08-20 US disclosed
WO-2009067081-A1 PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS ASTRAZENECA AB (SE) 2009-05-28 WO disclosed