Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.85 |
| ▸ | BRD4 | O60885 | 18/20 | 0.85 |
| ▸ | EP300 | Q09472 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17795055 | 0.92 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL17795036 | 0.91 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL17795263 | 0.89 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL17794910 | 0.89 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL17794852 | 0.89 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL17785873 | 0.89 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL17794839 | 0.89 | CREBBP (1.00) | CREBBPBRD4EP300 | |
| SCHEMBL17785768 | 0.88 | CREBBP (0.84) | CREBBPBRD4EP300 | |
| SCHEMBL17799337 | 0.87 | CREBBP (0.87) | CREBBPBRD4EP300 | |
| SCHEMBL17795048 | 0.84 | CREBBP (1.00) | CREBBPBRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531690-B | 4,5,6, 7-tetrahydro-1H-pyrazolo [4,3-c ] pyridin-3-amine compounds as CBP and/or EP300 inhibitors | 基因泰克公司 | 2020-11-06 | — | — | CN | disclosed |